Experimental Studies on Electroretinogram of Congenitally Diabetic KK Mice
نویسندگان
چکیده
منابع مشابه
Characteristics of diabetic osteopenia in KK-Ay diabetic mice.
We examined the bone mineral density (BMD) of the proximal region and the mid-diaphysis of the femur using dual energy X-ray absorption (DXA), the blood osteocalcin level and the blood glucose level every five weeks from 8 to 23 weeks old in KK-Ay diabetic mice. The BMD of the proximal region after 18 weeks old was significantly lower when compared with that at 8 weeks old (p<0.05), whereas the...
متن کاملStudies on lipogenesis in hereditary obese-hyperglycemic mice (KK strain).
Fatty acid synthesis in KK mouse, which exhibits a hereditary obese-hyperglycemic syndrome, was studied. Incorporation of [U-14C] glucose into liver fatty acid in vivo was more than four times higher in KK compared with control mice ( CF 1 ), but no significantly increased incorporation was observed into carcass fatty acid. Incorporation of [1-14C] acetate into liver fatty acid in vivo was also...
متن کاملGeneral survey of diabetic features of yellow KK mice.
Yellow KK mice, carrying the yellow obese gene (Ay), developed marked adiposity and diabetic symptoms in comparison with their control littermates, black KK mice. The blood glucose and circulating insulin levels were increased progressively from 5 weeks of age in yellow KK mice. Age dependent alterlations were also observed in pancreas and kidney. Namely, degranulation and glycogen infiltration...
متن کاملAntidiabetic activity of isoquercetin in diabetic KK -Ay mice
BACKGROUND Tartary buckwheat bran is an important natural source of quercetin and isoquercetin. Quercetin and isoquercetin are both powerful α-glucosidase inhibitors. Although the IC50 of isoquercetin as α-glucosidase inhibitor was much higher than that of quercetin, the bioavailability of isoquercetin was higher than that of quercetin. Hence, we are interested in the antidiabetic effect of iso...
متن کاملAntidiabetic effect of glycyrrhizin in genetically diabetic KK-Ay mice.
We, previously demonstrated that one shot administration of glycyrrhizin (Grz) reduced the postprandial blood glucose rise, using Std ddY mice. Subsequently, we evaluated the effects of long-term Grz treatment (2.7, 4.1 g/kg diet) on diabetic symptoms using genetically non-insulin dependent diabetic model mice (KK-Ay). Male KK-Ay mice were divided into 3 groups: the control group, 0.27% Grz die...
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ژورنال
عنوان ژورنال: The Journal of Kansai Medical University
سال: 1975
ISSN: 0022-8400
DOI: 10.5361/jkmu1956.27.2_286